YESSSESSSS
IM FINE WBYYY
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IM FINE WBYYY
WAIT DO U HAVE SCHOOL RN?
I'm okkk wydddddddddd
okoks
when dealing with um mutations, there's usually a change in the DNA involving it's base pairs (A, T, G, or U)
A can pair with T, or U
G should pair with C but thats a convo for another day
in this type of mutation, the original sequence (above the gene with insertion) is as shown.
When the mutation is caused, a G (yk the thing in red), is inserted. Everything after that G is shifted right. Therefore, the... yk... sigh. sequence changes in a way
you need three letters to create.. codons
looking back at this chart,
is 
THR.. or whatever
so
after ACA, there was AAG, the next codon. But since that G was added (yk.. bottom), it changed to GAA, which would be found at GLU
When trying to find these codons, you'd look for the first letter in the super left column, which in this case is G. The 2nd letter will be looked for at the top, which is A. the 3rd, is all the way to the right. You want to find where they meet to create the codon GAA, which is GLU
omg this is so hard. teaching i mean
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Whaaa? Soo spring break?
awh ok im in class
history
Ohhhh oki oki!!! when do ik when its deletion like ik its when like a letter isn't there yk but I still get stuck
mk now we're gonna look at this mutation example
On the left is where the original sequence is
you can see the DNA (CTT.. codon. remember that. ALSO blue sequence) is paired up with the mRNA (GAA.. the red. codon.) ALSO reference back to what I said earlier. A pairs with T (or U), C pairs with G... blah blah blah. So if I have C in the DNA, it'll have to be paired with G in the RNA but anyways moving on
The mrna is where we want to put our focus on at the moment
you can see the mrna is GAA, which can create the codon Glu
looking back at the original chart
we'll find it here
anyways
back to the mutation, if the base pair is changed in the DNA, like how it was changed from T to A
the mrna is changed. A cannot be paired up with A.
So, in this case, the mrna will be changed to U
OH THAT REMINDS ME
u can only be in MRNA, not DNA
this is so complicating im so sorry
but yes notice the change
NOW our codon is GUA
we have to look for it woohooo
As a result of the mutation, our new codon is Val
On the left is where the original sequence is
you can see the DNA (CTT.. codon. remember that. ALSO blue sequence) is paired up with the mRNA (GAA.. the red. codon.) ALSO reference back to what I said earlier. A pairs with T (or U), C pairs with G... blah blah blah. So if I have C in the DNA, it'll have to be paired with G in the RNA but anyways moving on
The mrna is where we want to put our focus on at the moment
you can see the mrna is GAA, which can create the codon Glu
looking back at the original chart
we'll find it here
anyways
back to the mutation, if the base pair is changed in the DNA, like how it was changed from T to A
the mrna is changed. A cannot be paired up with A.
So, in this case, the mrna will be changed to U
OH THAT REMINDS ME
u can only be in MRNA, not DNA
this is so complicating im so sorry
but yes notice the change
NOW our codon is GUA
we have to look for it woohooo
As a result of the mutation, our new codon is Val
and I'm very very grateful <3
my brain hurts
welcome to freshman year in an early college
uhhh
deletion..
then.. the sequence shifts left
try to imagine we js deleted the C under Thr
now the new sequence is AAAGAGAGGT
our new codons are AAA, GAG, AGG, and then we're left with a T, which can cause further issues in our mrna
ykw
i do not miss mr vaughn's class
i do not miss mr vaughn's class
*sigh* yes indeed
i js realized ves put "don't call D" in the msg of my sunoo plushie
im crying
im crying
loll
ok i sleep yes yum